book_cover_img The Korean Society of Marine Life Science Journal of Marine Life Science eISSN 2508-7134
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Year of Launching : 2016
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Doi Prefix : 10.23005/ksmls.

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ISSN : 2508-7134(Online)
Journal of Marine Life Science Vol.2 No.1 pp.34-38
DOI :

Effects of Thermal and Salinity Stress on Expression of FK506BP in the Red Seabream (Pagrus major)
참돔(Pagrus major)에서 온도 및 염분 스트레스가 FK506BP 발현에 미치는 영향

Byung Hwa Min1, Jeong-In Myeong2, Han Seung Kang3*
민병화1, 명정인2, 강한승3*
1Aquaculture Management Division, National Fisheries Research & Development Institute, Busan 46083, Korea
2Aquaculture Research Department, National Fisheries Research & Development Institute, Busan 46083, Korea
3Genome Research Department, MS BioLab, Daejeon 34576, Korea

1국립수산과학원 양식관리과
2국립수산과학원 전략양식부
3엠에스바이오랩 유전체연구부
Corresponding Author Han Seung Kang Genome Research Department, MS BioLab, Daejeon 34576, Korea E-mail : hanseungkang66@gmail.com

Abstract

FK506BP (FK506 binding protein 12) is a small peptide with a single FK506BP domain. It is involved in suppression of immune response, oxidative stress and inflammation. The purpose of this study was to investigate the gene expression of FK506BP in red seabream (Pagrus major) exposure to low water temperature (8℃, 33 psu) and low salinity (20℃, 10 psu). Results showed that, the expression of FK506BP was significantly increased in the experiment groups, such as low water temperature (8℃, 33 psu), and low salinity (20℃, 10 psu). These results suggest that FK506BP was played roles in biomarker gene on the environmental stress such as water temperature and salinity. FK506BP는 일명 FK506 binding protein 12이라 불리는 작은 펩티드로서 single 도메인을 가진 다. FK506BP는 면역반응 억제, 산화적 스트레스 및 염증과 관련이 있다. 본 연구의 목적은 참돔 (Pagrus major)을 저수온(8℃, 33 psu) 및 저염분(20℃, 10 psu) 상태에 노출시킨 후, FK506BP 유 전자의 발현을 관찰하는 것이다. 연구결과, FK506BP 유전자의 발현은 저수온(8℃, 33 psu) 및 저 염분(20℃, 10 psu)상태에서 유의적으로 증가하는 것으로 나타났다. 이 연구결과로서 FK506BP 유전자는 수온 및 염분 등의 환경 스트레스에 대한 생체지표유전자로서 역할을 한다고 제의 한다.

초록

 

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